Shoutbox Wannabe.

[Ninurta]

I saw this article and it made me think.

If my Chron's disease is due to an ancestor having survived the Black Death, maybe it is also why I did not get COVID. ?????

You might have Crohn’s disease, rheumatoid arthritis or lupus because your ancestor survived the Black Death, study says.

A team examined ancient DNA from the bones of Black Death survivors and found four genes associated with modern disorders.

https://fortune.com/2022/10/19/black-dea...tis-genes/

Could be. Many don't understand just how much influence genes have over not just physical traits like hair and eye color, but also strengths, vulnerabilities, and even emotional state. I've been laying off to make a thread on a discovery i read about a few nights ago - apparently, there is a particular codon that has been found in people in general, but which is missing from people who have psychic types of experiences.

Link 1

The results of pedigree and segregation analyses demonstrate that second sight seems consistent with an autosomal dominant inheritance pattern, especially for small family sizes. Though certain aspects of the data favoured a social and cultural model, it was argued that they were still consistent with second sight having an underlying genetic component. The importance of other studies examining the pedigrees of second sight in different cultures was stressed. If similar inheritance patterns were observed in disparate cultures, this would provide further scientific support for the view that second sight is hereditary. It was speculated that second sight may be part of a creative mental process and what may be hereditary is the way information is received and processed by the brain and expressed in different sensory modalities.

Link 2

It is commonly believed that psychic ability, like many mental and physical traits, runs in families. This suggests the presence of a genetic component. If such a component were found, it would constitute a biological marker of psychic ability and inform environmental or pharmacologic means of enhancing or suppressing this ability.

and, from the same link:

Results

Sequencing data were obtained for all samples, except for one in the control group that did not pass the quality controls and was not included in further analyses. After unblinding the datasets, none of the protein-coding sequences (i.e., exons) showed any variation that discriminated between cases and controls. However, a difference was observed in the intron (i.e., non-protein-coding region) adjacent to an exon in the TNRC18 gene (Trinucleotide Repeat-Containing Gene 18 Protein) on chromosome 7. This variation, an alteration of GG to GA, was found in 7 of 9 controls and was absent from all psychic cases.

I'm still trying to find the specific SNP mentioned, to see if it is one of the ones reported in commercial DNA testing. That might be both a blessing and a curse to those tested.

The Black Plague - Chron's DIsease-Lupus-rhewumatoid arthritis connection makes sense to me. Genes coding for an overactive immune system should provide protection from a lot of pestilential ailments, but when there is nothing there for the immune system to attack, it attacks it's own body, resulting in the afflictions listed. If 30% of the population died during the Plague, then the genes passed on through the living would be more likely to be the ones coding for that warp-drive immune system. That, in turn, would lead to a higher incidence of those autoimmune diseases in modern folks than was found in the general population before that culling.

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