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Nicotine and Menthol as Possible Treatments for SARS-CoV-2
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Although this particular subject is related to conspiracy surrounding the latest menthol cigarette ban, it really belongs in this forum. All the information in this post is from the National Institute of Health.

Although not technically a medical treatment, nicotine and menthol could possibly be used to treat COVID-19. At a molecular level, nicotine may help prevent a cytokine storm from COVID-19 and menthol may have a synergistic relationship with nicotine that boosts this effect. Below is information from the NIH on nicotine and menthol.

Quote:Nicotine can selectively reduce the inflammatory response in various infection states, including Legionella pneumophila and Chlamydia pneumoniae infection, via the cholinergic anti-inflammatory pathway [6]. Nicotine is an agonist at the α7 subunit of nicotinic acetylcholine (α7-nACh) receptors on innate immune cells such as macrophages. These receptors respond to acetylcholine from different sources, including other immune cells and the vagus nerve, and their activation causes suppression of pro-inflammatory cytokines. Nicotine is able to suppress the production of pro-inflammatory cytokines by mimicking the binding of acetylcholine . . .

In the absence of any effective treatment for COVID-19, further research as to whether nicotine replacement offers protection against severe SAR-CoV-2 infection in smokers is clearly essential. If the mechanisms through which nicotine may interact with the virus remain speculative, the effects of route of administration, duration, dosing and frequency of use of nicotine on any such interaction are unknown.

Above is evidence, from the NIH, that states "Nicotine is able to suppress the production of pro-inflammatory cytokines", but of course, "Smoking is bad and you must quit smoking!".

But what of menthol?

Quote:Menthol Enhances the Desensitization of Human α3β4 Nicotinic Acetylcholine Receptors

Abstract - The α3β4 nicotinic acetylcholine receptor (nAChR) subtype is widely expressed in the peripheral and central nervous systems, including in airway sensory nerves. The nAChR subtype transduces the irritant effects of nicotine in tobacco smoke and, in certain brain areas, may be involved in nicotine addiction and/or withdrawal. Menthol, a widely used additive in cigarettes, is a potential analgesic and/or counterirritant at sensory nerves and may also influence nicotine’s actions in the brain.

Menthol works on the nervous system reducing the irritating effects of nicotine and like nicotine, it also affects nicotinic acetylcholine receptors. I wonder what other synergistic effect it has on nicotine and what other receptors menthol can affect? Below are some more interesting facts from the NIH.

Quote:Menthol has been tested in humans mainly for its pharmaceutical properties, such as enhancement of lung and airway volume . . .

Aside from its cold-inducing sensation capabilities, menthol exhibits cytotoxic effects in cancer cells, induces reduction in malignant cell growth, and engages in synergistic excitation of GABA receptors and sodium ion channels resulting in analgesia.


It looks like the NIH knows all about the beneficial effects of nicotine and menthol when treating COVID. They know that nicotine can reduce a cytokine storm and menthol can open up the airways, reduce pain and is toxic to cancer cells. It seems that menthol cigarettes may be healthier than regular tobacco cigarettes and may have beneficial effects as a COVID treatment. I find it strange and suspicious how they don't talk about all this and want to ban menthol cigarettes.

Now for the conspiracy side of all this, let's have a look at these facts.

The majority of African Americans prefer menthol cigarettes.
The African American population has been hit hardest by COVID.
NIH studies have shown that nicotine and menthol have beneficial effects suitable for COVID treatments.
The NIH is the scientific authority on COVID and makes recommendations to the government on treatments.
The NIH states the need for more research on nicotine's beneficial effects on treating COVID but does none.
The government wants to ban menthol cigarettes because it disproportionately has negative affects on the health of African Americans.

What kind of conclusion can one come to when reviewing the facts from Faucci's NIH?


NIH Link 1
NIH Link 2
NIH Link 3


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Nicotine and Menthol as Possible Treatments for SARS-CoV-2 - by Michigan Swamp Buck - 05-02-2021, 05:13 PM

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